(Current league) Find and talk to Farrow, and do the event and talk to Farrow again
Kill Beira to loot and use Head of the Winter Wolf for +10% cold resistance
(Optional) Enter Mud Borrows, kill The Devourer for a Random Gem and go back
(Optional) Find an Abandoned Stash to get an Skill Gem Lvl 1
Enter Grelwood

Find, summon and talk to Una and the waypoint
Enter Grim Tangle, take the waypoint and go back
Enter The Red Vale, take the waypoint and go back
(Optional) Kill Gerung, the Brambleghast to get a Skill Gem Lvl 1
(Optional) Find a hut with a Cauldron for flasks and kill Areagne, Forgotten Witch for a Support Gem LvL 1
Enter Red Vale

Find the three Obelisks of Rust and loot Runed Girdle each time (The Rust King will spawn on the last one)
Teleport back to town

Talk to Lachlann the Lost
(Optional) Loot the Sarcophagus near a checkpoint for a guaranteed Ring
Find the Tomb of the Consort, kill Asinia, loot the Key Piece and teleport back
(Optional) In Tomb of the Consort, find a haunted Chest to kill a rare and get a Support Gem Lvl 1
Find the Mausoleum of the Praetor, kill Draven, loot the Key Piece and teleport back.
(Optional) In Mausoleum of the Praetor, find a Switch to click to take stairs to gold, loot and a Support Gem Lvl 1
Open the Memorial Gate next to Lachlann (after clicking the gate, you can "Respawn at checkpoint" to skip roleplay)
Kill Lachlann and loot the Ring
Teleport back to town

(Current league) Talk to Farrow
(Current league) Find the second Runestone to summon Farrow and talk to him
(Optional) Talk to Delwyn for the wisp event
(Optional) Do the Ritual event in the middle of the map then talk to Finn for a Skill Gem Lvl 4
(Optional) Do the small ritual event near a checkpoint for a Support Gem Lvl 1
Kill The Crowbell to loot Book of Specialisation, giving two passive points
Enter Freythorn, take waypoint and go back (follow the locusts after the ritual event to find the zone)
Enter Ogham Farmlands, take waypoint and go back (follow the road and signposts to find the zone)
Teleport to Freythorn

(Current league) Talk to Farrow
(Current league) Find the last Runestone of the act to summon Farrow and talk to him
Interact with Una's Lute Box in a house to loot Una's Lute (follow the road and behind blocking carts)
(Optional) Kill the rare dogs in the crop circle for a Skill Gem Lvl 4
Enter Ogham village, take the waypoint
(Current league) Teleport to Grelwood

(First character) Find the Smithing Tools in a house near a checkpoint to unlock Salvaging Bench
(Optional) Loot the Blacksmith's Chest in the same house for a Blank Rune (with a Lesser Rune as reward in town) and an Artificier's Orb
Kill The Executioner
Go upstairs, use the Lever and talk to Leitis
Enter The Manor Ramparts

(Optional) Click the Rope of the hanging man near a checkpoint for a Support Gem Lvl 1
Enter Oghman Manor